The Axl-Regulating Tumor Suppressor miR-34a Is Increased in ccRCC but Does Not Correlate with Axl mRNA or Axl Protein Levels

BACKGROUND: High expression of the receptor tyrosine kinase Axl is associated with poor prognosis in patients with Renal Cell Carcinoma (RCC), the most common malignancy of the kidney. The miR-34a has been shown to directly regulate Axl in cancer cells. The miR-34a is a mediator of p53-dependent tum...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Fritz, Helena K., Gustafsson, Anna, Ljungberg, Börje, Ceder, Yvonne, Axelson, Håkan, Dahlbäck, Björn
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546115/
https://ncbi.nlm.nih.gov/pubmed/26287733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135991
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