Expression of AIM2 is correlated with increased inflammation in chronic hepatitis B patients

BACKGROUND: The absent in melanoma 2 (AIM2), a cytosolic dsDNA inflammasome, can be activated by viral DNA to trigger caspase-1. Its role in immunopathology of chronic hepatitis B and C virus (HBV, HCV) infection is still largely unclear. In this study, the expression AIM2, and its downstream cytoki...

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Dettagli Bibliografici
Pubblicato in:Virol J
Autori principali: Han, Yongtao, Chen, Ziping, Hou, Ruiping, Yan, Daojie, Liu, Changhong, Chen, Shijun, Li, Xiaobo, Du, Wenjun
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545983/
https://ncbi.nlm.nih.gov/pubmed/26290184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-015-0360-y
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