Multimodal treatment of perianal fistulas in Crohn’s disease: seton versus anti-TNF versus advancement plasty (PISA): study protocol for a randomized controlled trial

BACKGROUND: Currently there is no guideline for the treatment of patients with Crohn’s disease and high perianal fistulas. Most patients receive anti-TNF medication, but no long-term results of this expensive medication have been described, nor has its efficiency been compared to surgical strategies...

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Detalhes bibliográficos
Publicado no:Trials
Main Authors: de Groof, E. Joline, Buskens, Christianne J., Ponsioen, Cyriel Y., Dijkgraaf, Marcel G. W., D’Haens, Geert R. A. M., Srivastava, Nidhi, van Acker, Gijs J. D., Jansen, Jeroen M., Gerhards, Michael F., Dijkstra, Gerard, Lange, Johan F. M., Witteman, Ben J. M., Kruyt, Philip M., Pronk, Apollo, van Tuyl, Sebastiaan A. C., Bodelier, Alexander, Crolla, Rogier M. P. H., West, Rachel L., Vrijland, Wietske W., Consten, Esther C. J., Brink, Menno A., Tuynman, Jurriaan B., de Boer, Nanne K. H., Breukink, Stephanie O., Pierik, Marieke J., Oldenburg, Bas, van der Meulen, Andrea E., Bonsing, Bert A., Spinelli, Antonino, Danese, Silvio, Sacchi, Matteo, Warusavitarne, Janindra, Hart, Ailsa, Yassin, Nuha A., Kennelly, Rory P., Cullen, Garret J., Winter, Desmond C., Hawthorne, A. Barney, Torkington, Jared, Bemelman, Willem A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545975/
https://ncbi.nlm.nih.gov/pubmed/26289163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-015-0831-x
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