Osteochondral tissue engineering using a biphasic collagen/GAG scaffold containing rhFGF18 or BMP-7 in an ovine model

BACKGROUND: The aim of this study was to investigate the effect of combining rhFGF18 or BMP-7 with a biphasic collagen/GAG osteochondral scaffold (Chondromimetic) on the repair of osteochondral defects in sheep. METHODS: Osteochondral defects (5.8x6mm) were created in the medial femoral condyle (MFC...

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Bibliographische Detailangaben
Veröffentlicht in:J Exp Orthop
Hauptverfasser: Getgood, Alan, Henson, Frances, Skelton, Carrie, Brooks, Roger, Guehring, Hans, Fortier, Lisa A, Rushton, Neil
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2014
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545804/
https://ncbi.nlm.nih.gov/pubmed/26914758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40634-014-0013-x
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