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Role of LFA-1 in the Activation and Trafficking of T-cells: Implications in the Induction of Chronic Colitis

The objectives of this study were to assess the role of LFA-1 in enteric antigen (EAg)-induced activation of T-cells in vitro and in vivo and to define the importance of this integrin in promoting trafficking of T-cells to the MLNs and colon. We found that EAg-pulsed dendritic cells (DCs) induced pr...

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Detalhes bibliográficos
Publicado no:Inflamm Bowel Dis
Main Authors: Koboziev, Iurii, Karlsson, Fridrik, Ostanin, Dmitry V., Gray, Laura, Davidson, Melissa, Zhang, Songlin, Grisham, Matthew B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545769/
https://ncbi.nlm.nih.gov/pubmed/22488891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.22947
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