Roles of two DNA-binding factors in replication, segregation and transcriptional repression mediated by a yeast silencer.

The HMR E silencer is required for SIR-dependent transcriptional repression of the silent mating-type locus, HMR. The silencer also behaves as an origin of replication (ARS element) and allows plasmids to replicate autonomously in yeast. The replication and segregation properties of these plasmids a...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Kimmerly, W, Buchman, A, Kornberg, R, Rine, J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC454575/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3046937/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1988.tb03064.x
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