Bacterial membrane disrupting dodecapeptide SC4 improves survival of mice challenged with Pseudomonas aeruginosa

BACKGROUND: Dodecapeptide SC4 is a broad-spectrum bactericidal agent that functions by disintegrating bacterial membranes and neutralizing endotoxins. For insight into which SC4 amino acids are functionally important, we assessed Gram-negative bactericidal effects in structure-activity relationships...

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Detaylı Bibliyografya
Yayımlandı:Biochim Biophys Acta
Asıl Yazarlar: Dings, Ruud P.M., Haseman, Judith R., Leslie, Dan B., Luong, Mike, Dunn, David L., Mayo, Kevin H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545587/
https://ncbi.nlm.nih.gov/pubmed/23403135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2013.02.002
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