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In silico model-based inference: an emerging approach for inverse problems in engineering better medicines

Identifying the network of biochemical interactions that underpin disease pathophysiology is a key hurdle in drug discovery. While many components involved in these biological processes are identified, how components organize differently in health and disease remains unclear. In chemical engineering...

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Publicat a:Curr Opin Chem Eng
Autors principals: Klinke, David J., Birtwistle, Marc R.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545575/
https://ncbi.nlm.nih.gov/pubmed/26309811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coche.2015.07.006
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