Production of anti TNF-α antibodies in eukaryotic cells using different combinations of vectors carrying heavy and light chains

Tumor necrosis factor-α (TNF-α) plays a key role in rheumatoid arthritis and some other autoimmune diseases. Therapy with anti-TNF-α recombinant antibodies (Ab) appears to be highly effective. Production of new hyper-producing eukaryotic cell lines can decrease the treatment cost, which currently is...

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Publicat a:Cytotechnology
Autors principals: Balabashin, Dmitriy, Kovalenko, Elena, Toporova, Viktoria, Aliev, Teimur, Panina, Anna, Svirshchevskaya, Elena, Dolgikh, Dmitry, Kirpichnikov, Mikhail
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2014
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Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545435/
https://ncbi.nlm.nih.gov/pubmed/24939591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-014-9714-3
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