Three chemically distinct types of oxidants formed by iron-mediated Fenton reactions in the presence of DNA.
Exposure of Escherichia coli to H2O2 leads to two kinetically distinguishable modes of killing: mode I killing occurs maximally near 2 mM H2O2, whereas mode II killing is essentially independent of H2O2 concentrations up to 20 mM. A major portion of H2O2 toxicity is attributed to DNA damage caused b...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45453/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7809055/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.26.12438 |
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