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Association of Genetic Variation in the Transforming Growth Factor β-1 Gene with Serum Levels and Risk of Colorectal Neoplasia

In the normal intestinal epithelium transforming growth factor β-1 (TGFβ-1) acts as a growth inhibitor, but in malignant cells it may act as a tumor promoter. However, only limited information is available on genetic variation in the TGFB1 gene and its relationship to circulating levels and risk of...

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Vydáno v:Cancer Res
Hlavní autoři: Saltzman, Barbara S., Yamamoto, Jennifer F., Decker, Robert, Yokochi, Lance, Theriault, Andre G., Vogt, Thomas M., Le Marchand, Loïc
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545251/
https://ncbi.nlm.nih.gov/pubmed/18281501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-2144
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