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Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for In Vivo Phenotyping and Drug Monitoring

Several in vivo pre-clinical studies in Polycystic Kidney Disease (PKD) utilize orthologous rodent models to identify and study the genetic and molecular mechanisms responsible for the disease, and are very convenient for rapid drug screening and testing of promising therapies. A limiting factor in...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Irazabal, Maria V., Mishra, Prasanna K., Torres, Vicente E., Macura, Slobodan I.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544983/
https://ncbi.nlm.nih.gov/pubmed/26132821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52757
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