Chick Heart Invasion Assay for Testing the Invasiveness of Cancer Cells and the Activity of Potentially Anti-invasive Compounds

The goal of the chick heart assay is to offer a relevant organ culture method to study tumor invasion in three dimensions. The assay can distinguish between invasive and non-invasive cells, and enables study of the effects of test compounds on tumor invasion. Cancer cells - either as aggregates or s...

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Bibliographic Details
Published in:J Vis Exp
Main Authors: Bracke, Marc E., Roman, Bart I., Stevens, Christian V., Mus, Liselot M., Parmar, Virinder S., De Wever, Olivier, Mareel, Marc M.
Format: Artigo
Language:Inglês
Published: MyJove Corporation 2015
Subjects:
Medicine
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544965/
https://ncbi.nlm.nih.gov/pubmed/26131648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52792
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