The role of beta-hydroxyaspartate and adjacent carboxylate residues in the first EGF domain of human factor IX.

beta-Hydroxyaspartic acid is a post-translationally modified amino acid found in a number of plasma proteins in a domain homologous to epidermal growth factor. Its presence can be correlated with a high affinity Ca2+ binding site, with a dissociation constant of 10-100 microM. We describe a system f...

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Hauptverfasser: Rees, D J, Jones, I M, Handford, P A, Walter, S J, Esnouf, M P, Smith, K J, Brownlee, G G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1988
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC454485/
https://ncbi.nlm.nih.gov/pubmed/3262057
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