The use of chromosomal translocations to study human immunoglobulin gene organization: mapping DH segments within 35 kb of the C mu gene and identification of a new DH locus.

We have studied the Burkitt's lymphoma cell line Daudi which carries the translocation t(8;14). The breakpoint of this translocation on the 14q+ chromosome occurs near to a rearranged DH-JH join, and the actual chromosome junction is a few hundred base pairs upstream of the joined DH element. T...

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Autores principales: Buluwela, L, Albertson, D G, Sherrington, P, Rabbitts, P H, Spurr, N, Rabbitts, T H
Formato: Artigo
Lenguaje:Inglês
Publicado: 1988
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC454475/
https://ncbi.nlm.nih.gov/pubmed/3138112
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