The use of chromosomal translocations to study human immunoglobulin gene organization: mapping DH segments within 35 kb of the C mu gene and identification of a new DH locus.

We have studied the Burkitt's lymphoma cell line Daudi which carries the translocation t(8;14). The breakpoint of this translocation on the 14q+ chromosome occurs near to a rearranged DH-JH join, and the actual chromosome junction is a few hundred base pairs upstream of the joined DH element. The nu...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Buluwela, L, Albertson, D G, Sherrington, P, Rabbitts, P H, Spurr, N, Rabbitts, T H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC454475/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3138112/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1988.tb03039.x
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