Segmental flexibility and complement fixation of genetically engineered chimeric human, rabbit and mouse antibodies.

We generated a family of chimeric immunoglobulin G (IgG) molecules having identical antigen-combining sites for the dansyl (DNS) hapten, in conjunction with nine heavy chain constant (CH) regions. This family of antibody molecules allows comparison of CH dependent properties independent of possible...

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Detalhes bibliográficos
Main Authors: Dangl, J L, Wensel, T G, Morrison, S L, Stryer, L, Herzenberg, L A, Oi, V T
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC454472/
https://ncbi.nlm.nih.gov/pubmed/3138110
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