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Immune Cells Exploit a Neural Circuit to Enter the CNS

Multiple sclerosis (MS) is associated with the appearance of autoreactive T cells in the central nervous system. Using a mouse model of MS, Arima et al. now show that this attack begins at a specific spinal cord location. T cell entry into the CNS is regulated by a reflex neural circuit originating...

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Vydáno v:Cell
Hlavní autor: Tracey, Kevin J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544704/
https://ncbi.nlm.nih.gov/pubmed/22304908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.01.025
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