Complete structure and organization of immunoglobulin heavy chain constant region genes in a phylogenetically primitive vertebrate.

Immunoglobulin (Ig) gene organization in Heterodontus francisci (horned shark), a phylogenetically primitive vertebrate, is unique. Homologous Ig heavy chain variable (VH) and constant region (CH) specific probes were used to screen a spleen cDNA library constructed in lambda gt11. Both secretory (S...

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Pubblicato in:	EMBO J
Autori principali:	Kokubu, F, Hinds, K, Litman, R, Shamblott, M J, Litman, G W
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 1988
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC454470/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3138109/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1988.tb03036.x
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