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Inhibition of 14-3-3 Proteins Leads to Schizophrenia-Related Behavioral Phenotypes and Synaptic Defects in Mice

BACKGROUND: The 14-3-3 family of proteins is implicated in the regulation of several key neuronal processes. Previous human and animal studies have suggested an association between 14-3-3 dysregulation and schizophrenia. METHODS: We characterized the behavioral and functional changes in the transgen...

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Detalhes bibliográficos
Publicado no:Biol Psychiatry
Main Authors: Foote, Molly, Qiao, Haifa, Graham, Kourtney, Wu, Yuying, Zhou, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544659/
https://ncbi.nlm.nih.gov/pubmed/25863357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2015.02.015
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