Development of telmisartan in the therapy of spinal cord injury: pre-clinical study in rats

BACKGROUND: Decrease of peroxisome proliferator-activated receptors-δ (PPARδ) expression has been observed after spinal cord injury (SCI). Increase of PPARδ may improve the damage in SCI. Telmisartan, the antihypertensive agent, has been mentioned to increase the expression of PPARδ. Thus, we are go...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Drug Des Devel Ther
Main Authors: Lin, Chien-Min, Tsai, Jo-Ting, Chang, Chen Kuei, Cheng, Juei-Tang, Lin, Jia-Wei
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2015
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544623/
https://ncbi.nlm.nih.gov/pubmed/26316709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S86616
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