Phase II trial of metformin and paclitaxel for patients with gemcitabine-refractory advanced adenocarcinoma of the pancreas

BACKGROUND: In patients with adenocarcinoma of the pancreas, there are no standard second-line regimens. Many pre-clinical studies have shown that metformin alone or when combined with paclitaxel has antitumour effects on this tumour. We have tested here the combination of paclitaxel and metformin f...

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Detalhes bibliográficos
Publicado no:Ecancermedicalscience
Main Authors: Braghiroli, Maria Ignez, de Celis Ferrari, Anezka C R, Pfiffer, Tulio Eduardo, Alex, Alexandra Kichfy, Nebuloni, Daniela, Carneiro, Allyne S, Caparelli, Fernanda, Senna, Luiz, Lobo, Juliana, Hoff, Paulo Marcelo, Riechelmann, Rachel P
Formato: Artigo
Idioma:Inglês
Publicado em: Cancer Intelligence 2015
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544571/
https://ncbi.nlm.nih.gov/pubmed/26316884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3332/ecancer.2015.563
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