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Point mutations destabilizing a precursor protein enhance its post-translational import into mitochondria.

In order to study the role of protein unfolding during post-translational protein import into mitochondria, we destabilized the structure of a mitochondrial precursor protein by site-directed mutagenesis. The precursor consisted of the first 16 residues of the yeast cytochrome oxidase subunit IV pre...

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Autors principals: Vestweber, D, Schatz, G
Format: Artigo
Idioma:Inglês
Publicat: 1988
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC454449/
https://ncbi.nlm.nih.gov/pubmed/2841113
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