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Copy number variation in exportin-4 (XPO4) gene and its association with histological severity of non-alcoholic fatty liver disease

A recent genome-wide copy number (CNV) scan identified a 13q12.11 duplication in the exportin-4 (XPO4) gene to be associated with non-alcoholic steatohepatitis (NASH). We sought to confirm the finding in a larger cohort and to assess the serum XPO4 pattern in a broad spectrum of non-alcoholic fatty...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Zain, Shamsul Mohd, Mohamed, Zahurin, Pirmohamed, Munir, Tan, Hwa Li, Alshawsh, Mohammed Abdullah, Mahadeva, Sanjiv, Chan, Wah-Kheong, Mustapha, Nik Raihan Nik, Mohamed, Rosmawati
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543956/
https://ncbi.nlm.nih.gov/pubmed/26293807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13306
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