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Imaging Fibrosis and Separating Collagens using Second Harmonic Generation and Phasor Approach to Fluorescence Lifetime Imaging

In this paper we have used second harmonic generation (SHG) and phasor approach to auto fluorescence lifetime imaging (FLIM) to obtain fingerprints of different collagens and then used these fingerprints to observe bone marrow fibrosis in the mouse femur. This is a label free approach towards fast a...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ranjit, Suman, Dvornikov, Alexander, Stakic, Milka, Hong, Suk-Hyun, Levi, Moshe, Evans, Ronald M., Gratton, Enrico
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543938/
https://ncbi.nlm.nih.gov/pubmed/26293987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13378
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