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A spliced Epstein-Barr virus gene expressed in immortalized lymphocytes is created by circularization of the linear viral genome.

Epstein-Barr virus (EBV) immortalizes B-lymphocytes efficiently in vitro and in most or all of the cells a latent infection is established. Only a few viral genes are expressed during latency and these apparently maintain cell immortalization by EBV. A 1.9 kb cDNA clone of an EBV mRNA has been isola...

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Bibliographic Details
Published in:EMBO J
Main Authors: Laux, G, Perricaudet, M, Farrell, P J
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1988
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC454390/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2840285/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1988.tb02874.x
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