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Rescue and Stabilization of Acetylcholinesterase in Skeletal Muscle by N-terminal Peptides Derived from the Noncatalytic Subunits

The vast majority of newly synthesized acetylcholinesterase (AChE) molecules do not assemble into catalytically active oligomeric forms and are rapidly degraded intracellularly by the endoplasmic reticulum-associated protein degradation pathway. We have previously shown that AChE in skeletal muscle...

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Pubblicato in:J Biol Chem
Autori principali: Ruiz, Carlos A., Rossi, Susana G., Rotundo, Richard L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543640/
https://ncbi.nlm.nih.gov/pubmed/26139603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.653741
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