The GPR 55 agonist, L-α-lysophosphatidylinositol, mediates ovarian carcinoma cell-induced angiogenesis

BACKGROUND AND PURPOSE: Highly vascularized ovarian carcinoma secretes the putative endocannabinoid and GPR55 agonist, L-α-lysophosphatidylinositol (LPI), into the circulation. We aimed to assess the involvement of this agonist and its receptor in ovarian cancer angiogenesis. EXPERIMENTAL APPROACH:...

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Publicat a:Br J Pharmacol
Autors principals: Hofmann, Nicole A, Yang, Jiang, Trauger, Sunia A, Nakayama, Hironao, Huang, Lan, Strunk, Dirk, Moses, Marsha A, Klagsbrun, Michael, Bischoff, Joyce, Graier, Wolfgang F
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Ltd 2015
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543616/
https://ncbi.nlm.nih.gov/pubmed/25989290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13196
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