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Contemporary considerations for constructing a Genetic Risk Score: An Empirical Approach
Genetic Risk Scores are an increasingly popular tool for summarizing the cumulative risk of a set of SNPs with disease. Typically only the set of the SNPs that have reached genome-wide significance compose these scores. However recent work suggests that including additional SNPs may aid risk assessm...
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Published in: | Genet Epidemiol |
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Main Authors: | , , , |
Format: | Artigo |
Language: | Inglês |
Published: |
2015
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4543537/ https://ncbi.nlm.nih.gov/pubmed/26198599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21912 |
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