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Contemporary considerations for constructing a Genetic Risk Score: An Empirical Approach

Genetic Risk Scores are an increasingly popular tool for summarizing the cumulative risk of a set of SNPs with disease. Typically only the set of the SNPs that have reached genome-wide significance compose these scores. However recent work suggests that including additional SNPs may aid risk assessm...

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Bibliographic Details
Published in:Genet Epidemiol
Main Authors: Goldstein, Benjamin A., Yang, Lingyao, Salfati, Elias, Assimes, Themistoclies L.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543537/
https://ncbi.nlm.nih.gov/pubmed/26198599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21912
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