Isoflurane Favorably Modulates Guanosine Triphosphate Cyclohydrolase-1 and Endothelial Nitric Oxide Synthase during Myocardial Ischemia and Reperfusion Injury in Rats

BACKGROUND: We investigated the hypothesis that isoflurane modulates NO synthesis and protection against myocardial infarction through time-dependent changes in expression of key NO regulatory proteins, guanosine triphosphate cyclohydrolase (GTPCH) -1, the rate-limiting enzyme involved in the biosyn...

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Bibliografske podrobnosti
izdano v:Anesthesiology
Main Authors: Baotic, Ines, Weihrauch, Dorothee, Procknow, Jesse, Vasquez-Vivar, Jeanette, Ge, Zhi-Dong, Sudhakaran, Shaan, Warltier, David C., Kersten, Judy R.
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543441/
https://ncbi.nlm.nih.gov/pubmed/26192027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000778
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