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Reciprocal Regulation of Substance P and IL-12/IL-23 and the Associated Cytokines, IFNγ/IL-17: A Perspective on the Relevance of This Interaction to Multiple Sclerosis
The neuropeptide substance P (SP) exhibits cytokine-like properties and exerts different effects in autoimmune inflammation. Various immune cells express SP and its neurokinin-1 receptor (NK1R) isoforms. A role for SP has been demonstrated in a number of autoimmune conditions, including multiple scl...
Kaydedildi:
Yayımlandı: | J Neuroimmune Pharmacol |
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Asıl Yazarlar: | , , , , , , , , , , , |
Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
Springer US
2015
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4543419/ https://ncbi.nlm.nih.gov/pubmed/25690155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-015-9589-x |
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