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Use of the mTOR inhibitor everolimus in a patient with multiple manifestations of tuberous sclerosis complex including epilepsy

Tuberous sclerosis complex (TSC) is a genetic disease in which overactivation of mechanistic target of rapamycin (mTOR) signaling leads to the growth of benign hamartomas in multiple organs, including the brain, and is associated with a high rate of epilepsy and neurological deficits. The mTOR inhib...

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Detalles Bibliográficos
Publicado en:Epilepsy Behav Case Rep
Autor Principal: Wheless, James W.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543076/
https://ncbi.nlm.nih.gov/pubmed/26543807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebcr.2015.06.008
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