β-Lactam combinations with daptomycin provide synergy against vancomycin-resistant Enterococcus faecalis and Enterococcus faecium

OBJECTIVES: Enterococcus faecalis (Efc) and Enterococcus faecium (Efm) are frequently resistant to vancomycin and β-lactams (BLs). In vitro data suggest synergy between several BLs and glycopeptides or lipopeptides against resistant pathogens. Our objective was to conduct combination MIC and time–ki...

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Vydáno v:J Antimicrob Chemother
Hlavní autoři: Smith, Jordan R., Barber, Katie E., Raut, Animesh, Aboutaleb, Mostafa, Sakoulas, George, Rybak, Michael J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542582/
https://ncbi.nlm.nih.gov/pubmed/25645208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkv007
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