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Intravenous Bone Marrow Stem Cell Grafts Preferentially Migrate to Spleen and Abrogate Chronic Inflammation in Stroke

BACKGROUND AND PURPOSE—: Adult stem cell therapy is an experimental stroke treatment. Here, we assessed homing and anti-inflammatory effects of bone marrow stromal cells (hBMSCs) in chronic stroke. METHODS—: At 60 days post stroke, adult Sprague–Dawley rats received intravenous hBMSCs (4×10(6) label...

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Detalhes bibliográficos
Publicado no:Stroke
Main Authors: Acosta, Sandra A., Tajiri, Naoki, Hoover, Jaclyn, Kaneko, Yuji, Borlongan, Cesar V.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542567/
https://ncbi.nlm.nih.gov/pubmed/26219646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.115.009854
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