Adult hippocampal neurogenesis and pattern separation in DG: a role for feedback inhibition in modulating sparseness to govern population-based coding

The dentate gyrus (DG) of mammals harbors neural stem cells that generate new dentate granule cells (DGCs) throughout life. Behavioral studies using the contextual fear discrimination paradigm have found that selectively augmenting or blocking adult hippocampal neurogenesis enhances or impairs discr...

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Bibliographic Details
Published in:Front Syst Neurosci
Main Authors: McAvoy, Kathleen, Besnard, Antoine, Sahay, Amar
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2015
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542503/
https://ncbi.nlm.nih.gov/pubmed/26347621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsys.2015.00120
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