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Complex correlation between excitatory amino acid-induced increase in the intracellular Ca2+ concentration and subsequent loss of neuronal function in individual neocortical neurons in culture.

Primary cultures of cerebral cortical neurons and single-cell imaging of intracellular free Ca2+ concentration ([Ca2+]i) with the ratiometric dye fura-2 were used to assess excitatory amino acid (EAA)-induced neurotoxicity; the loss of neuronal function as defined by the ability of the cells to resp...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Witt, M R, Dekermendjian, K, Frandsen, A, Schousboe, A, Nielsen, M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45425/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7527559/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.25.12303
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