Metabolic Syndrome Abolishes Glucagon-Like Peptide 1 Receptor Agonist Stimulation of SERCA in Coronary Smooth Muscle

Metabolic syndrome (MetS) doubles the risk of adverse cardiovascular events. Glucagon-like peptide 1 (GLP-1) receptor agonists induce weight loss, increase insulin secretion, and improve glucose tolerance. Studies in healthy animals suggest cardioprotective properties of GLP-1 receptor agonists, per...

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Vydáno v:Diabetes
Hlavní autoři: Dineen, Stacey L., McKenney, Mikaela L., Bell, Lauren N., Fullenkamp, Allison M., Schultz, Kyle A., Alloosh, Mouhamad, Chalasani, Naga, Sturek, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2015
Témata:
Pharmacology and Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542436/
https://ncbi.nlm.nih.gov/pubmed/25845661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-1790
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