Selective Involvement of the Checkpoint Regulator VISTA in Suppression of B-Cell, but Not T-Cell, Responsiveness by Monocytic Myeloid-Derived Suppressor Cells from Mice Infected with an Immunodeficiency-Causing Retrovirus

Inhibition of T-cell responses in tumor microenvironments by myeloid-derived suppressor cells (MDSCs) is widely accepted. We demonstrated augmentation of monocytic MDSCs whose suppression of not only T-cell, but also B-cell, responsiveness paralleled the immunodeficiency during LP-BM5 retrovirus inf...

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Bibliographic Details
Published in:J Virol
Main Authors: Green, Kathy A., Wang, Li, Noelle, Randolph J., Green, William R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542392/
https://ncbi.nlm.nih.gov/pubmed/26157131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00888-15
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