Deregulation of hamster fibroblast proliferation by mutated ras oncogenes is not mediated by constitutive activation of phosphoinositide-specific phospholipase C.

Stable expression of high levels of activated forms of Haras (T24) or v-Ki-ras by transfection of Chinese hamster lung fibroblasts (CCL39) yielded cells highly tumorigenic in nude mice. Two classes of transformed cells were distinguished, one with moderate p21 expression (10-fold increased) had reta...

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Опубликовано в::	EMBO J
Главные авторы:	Seuwen, K, Lagarde, A, Pouysségur, J
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Nature Publishing Group 1988
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC454238/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2834200/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1988.tb02796.x
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