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HIV-1 Cell-Free and Cell-to-Cell Infections Are Differentially Regulated by Distinct Determinants in the Env gp41 Cytoplasmic Tail

The HIV-1 envelope (Env) glycoprotein mediates viral entry during both cell-free and cell-to-cell infection of CD4(+) T cells. The highly conserved long cytoplasmic tail (CT) of Env is required in a cell type-dependent manner for optimal infectivity of cell-free virus. To probe the role of the CT in...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Durham, Natasha D., Chen, Benjamin K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542346/
https://ncbi.nlm.nih.gov/pubmed/26136566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00655-15
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