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Id2 deletion attenuates Apc-deficient ileal tumor formation

The expression level of inhibitor of DNA binding 2 (Id2) is increased in colorectal carcinomas and is positively correlated with poor prognosis. However, the functional significance of Id2 in intestinal tumorigenesis has not been fully defined using genetic approaches. Here, we show that Id2 promote...

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Bibliografiska uppgifter
I publikationen:Biol Open
Huvudupphovsmän: Biyajima, Kyoko, Kakizaki, Fumihiko, Shen, Xiaodong, Mori, Kentaro, Sugai, Manabu, Taketo, M. Mark, Yokota, Yoshifumi
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Company of Biologists 2015
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542283/
https://ncbi.nlm.nih.gov/pubmed/26163528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.012252
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