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Inhaled Nitric Oxide as an Adjunctive Treatment for Cerebral Malaria in Children: A Phase II Randomized Open-Label Clinical Trial

Background. Children with cerebral malaria (CM) have high rates of mortality and neurologic sequelae. Nitric oxide (NO) metabolite levels in plasma and urine are reduced in CM. Methods. This randomized trial assessed the efficacy of inhaled NO versus nitrogen (N(2)) as an adjunctive treatment for CM...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Mwanga-Amumpaire, Juliet, Carroll, Ryan W., Baudin, Elisabeth, Kemigisha, Elisabeth, Nampijja, Dorah, Mworozi, Kenneth, Santorino, Data, Nyehangane, Dan, Nathan, Daniel I., De Beaudrap, Pierre, Etard, Jean-François, Feelisch, Martin, Fernandez, Bernadette O., Berssenbrugge, Annie, Bangsberg, David, Bloch, Kenneth D., Boum, Yap, Zapol, Warren M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542141/
https://ncbi.nlm.nih.gov/pubmed/26309894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofv111
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