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Optimising plasma levels of clozapine during metabolic interactions: a review and case report with adjunct rifampicin treatment

BACKGROUND: Clozapine is the only licensed medication for treatment-resistant schizophrenia. The metabolism of clozapine is affected by multiple pharmacokinetic interactions, so the co-administration of adjunct medications can have a significant clinical effect. The anti- tuberculosis medication rif...

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Detalhes bibliográficos
Publicado no:BMC Psychiatry
Main Authors: Gee, Siobhan, Dixon, Thomas, Docherty, Mary, Shergill, Sukhwinder S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542109/
https://ncbi.nlm.nih.gov/pubmed/26265348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12888-015-0536-4
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