GATA2 deficiency in children and adults with severe pulmonary alveolar proteinosis and hematologic disorders

BACKGROUND: The majority of cases with severe pulmonary alveolar proteinosis (PAP) are caused by auto-antibodies against GM-CSF. A multitude of genetic and exogenous causes are responsible for few other cases. Goal of this study was to determine the prevalence of GATA2 deficiency in children and adu...

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Pubblicato in:BMC Pulm Med
Autori principali: Griese, Matthias, Zarbock, Ralf, Costabel, Ulrich, Hildebrandt, Jenna, Theegarten, Dirk, Albert, Michael, Thiel, Antonia, Schams, Andrea, Lange, Joanna, Krenke, Katazyrna, Wesselak, Traudl, Schön, Carola, Kappler, Matthias, Blum, Helmut, Krebs, Stefan, Jung, Andreas, Kröner, Carolin, Klein, Christoph, Campo, Ilaria, Luisetti, Maurizio, Bonella, Francesco
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542098/
https://ncbi.nlm.nih.gov/pubmed/26264606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-015-0083-2
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