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A general approach for chemical labeling and rapid, spatially controlled protein inactivation

Chemical labeling of proteins inside of living cells can enable studies of the location, movement, and function of proteins in vivo. Here we demonstrate an approach for chemical labeling of proteins that uses the high-affinity interaction between an FKBP12 mutant (F36V) and a synthetic, engineered l...

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Detalhes bibliográficos
Main Authors: Marks, Kevin M., Braun, Patrick D., Nolan, Garry P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC454201/
https://ncbi.nlm.nih.gov/pubmed/15218100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401609101
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