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CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: Induction of cytokine release and cytotoxicity against tumors and dendritic cells

Toll-like receptors (TLRs) are pattern-recognition receptors responible for triggering cells of innate immunity. In this study we investigated the expression and function of TLRs 3 and 9 in human natural killer (NK) cells. In the presence of IL-12, freshly isolated NK cells responded to double-stran...

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Hlavní autoři: Sivori, Simona, Falco, Michela, Chiesa, Mariella Della, Carlomagno, Simona, Vitale, Massimo, Moretta, Lorenzo, Moretta, Alessandro
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2004
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC454174/
https://ncbi.nlm.nih.gov/pubmed/15218108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403744101
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