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SOX30, a novel epigenetic silenced tumor suppressor, promotes tumor cell apoptosis by transcriptional activating p53 in lung cancer

Although members of SOX family have been well documented for their essential roles in embryonic development, cell proliferation and disease, the functional role and molecular mechanism of SOX30 in cancer are largely unexplored. Here, we first identified SRY-box containing gene 30 (SOX30) as a novel...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Han, F, Liu, W, Jiang, X, Shi, X, Yin, L, Ao, L, Cui, Z, Li, Y, Huang, C, Cao, J, Liu, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4541146/
https://ncbi.nlm.nih.gov/pubmed/25435374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.370
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