Less Frequent and Less Severe Flu-Like Syndrome in Interferon Beta-1a Treated Multiple Sclerosis Patients with at Least One Allele Bearing the G>C Polymorphism at Position -174 of the IL-6 Promoter Gene

One of the most common adverse event of interferon beta (IFNβ) therapy for multiple sclerosis is flu-like syndrome (FLS), which has been reportedly related to increased levels of cytokines such as interleukin 6 (IL-6) and tumor necrosis factor-alpha (TNF-α). Average cytokine levels can be affected b...

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Vydáno v:PLoS One
Hlavní autoři: Bertoli, Diego, Serana, Federico, Sottini, Alessandra, Cordioli, Cinzia, Maimone, Davide, Amato, Maria Pia, Centonze, Diego, Florio, Ciro, Puma, Elisa, Capra, Ruggero, Imberti, Luisa
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540473/
https://ncbi.nlm.nih.gov/pubmed/26285213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135441
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