Impact of AMP-Activated Protein Kinase α1 Deficiency on Tissue Injury following Unilateral Ureteral Obstruction

BACKGROUND: AMP-activated protein kinase (Ampk) is a sensor of the cellular energy status and a powerful regulator of metabolism. Activation of Ampk was previously shown to participate in monocyte-to-fibroblast transition and matrix protein production in renal tissue. Thus, the present study explore...

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Bibliographic Details
Published in:PLoS One
Main Authors: Mia, Sobuj, Federico, Giuseppina, Feger, Martina, Pakladok, Tatsiana, Meissner, Adrian, Voelkl, Jakob, Groene, Hermann-Josef, Alesutan, Ioana, Lang, Florian
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540418/
https://ncbi.nlm.nih.gov/pubmed/26285014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135235
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