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Mouse models of advanced spontaneous metastasis for experimental therapeutics

An enduring problem in cancer research is the failure to reproduce highly encouraging preclinical therapeutic findings using transplanted or spontaneous primary tumours in mice in clinical trials of patients with advanced metastatic disease. There are several reasons for this, including the failure...

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Detalhes bibliográficos
Publicado no:Nat Rev Cancer
Main Authors: Francia, Giulio, Cruz-Munoz, William, Man, Shan, Xu, Ping, Kerbel, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540342/
https://ncbi.nlm.nih.gov/pubmed/21258397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3001
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