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Telomerase Dysregulation in the Hippocampus of a Rat Model of Depression: Normalization by Lithium

BACKGROUND: Telomeres are protective DNA-protein complexes at the ends of each chromosome, maintained primarily by the enzyme telomerase. Shortening of the blood leukocyte telomeres is associated with aging, several chronic diseases, and stress, eg, major depression. Hippocampus is pivotal in the re...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Neuropsychopharmacol
Hauptverfasser: Wei, Ya Bin, Backlund, Lena, Wegener, Gregers, Mathé, Aleksander A, Lavebratt, Catharina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540104/
https://ncbi.nlm.nih.gov/pubmed/25618407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyv002
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